Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917298 | Molecular Immunology | 2013 | 5 Pages |
Abstract
⺠Folding, peptide binding, and transport rates differ markedly between MHC class I allotypes. ⺠It is important to understand class I maturation and transport as a contribution to immunodominance. ⺠Pulse-chase experiments in principle offer much information on folding, maturation, and ER-Golgi transport of class I. ⺠The review demonstrates their potential and advises how to avoid common pitfalls.
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Authors
Susanne Fritzsche, Sebastian Springer,