Article ID Journal Published Year Pages File Type
5917388 Molecular Immunology 2012 7 Pages PDF
Abstract
► Targeting a protein to UFD or N-end proteasome pathway lead to in its degradation. ► Targeting antigen to UFD resulted in better cytotoxic response than N-end pathway. ► Targeting antigen to UFD or N-end proteasome pathway caused tumour regression. ► Co-immunization with ubiquitin-TAA and TAA resulted in tumour protection. ► Co-immunization with ubiquitin-TAA and TAA resulted in TH1 immunity.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
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