Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917413 | Molecular Immunology | 2012 | 9 Pages |
Abstract
⺠We examined the mechanistic details of ESAT-6 triggered COX-2 expression. ⺠ESAT-6 triggers COX-2 expression in TLR2 dependent manner. ⺠ESAT-6 induced COX-2 expression involves cross-talk of PI3K and MAPK signaling axis. ⺠COX-2 expression is dependent on coordinated activation of NF-κB and AP-1.
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Authors
Senthil Kumar A, Kushagra Bansal, Sahana Holla, Shalu Verma-Kumar, Pawan Sharma, Kithiganahalli Narayanaswamy Balaji,