Article ID Journal Published Year Pages File Type
5917413 Molecular Immunology 2012 9 Pages PDF
Abstract
► We examined the mechanistic details of ESAT-6 triggered COX-2 expression. ► ESAT-6 triggers COX-2 expression in TLR2 dependent manner. ► ESAT-6 induced COX-2 expression involves cross-talk of PI3K and MAPK signaling axis. ► COX-2 expression is dependent on coordinated activation of NF-κB and AP-1.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Authors
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