Article ID Journal Published Year Pages File Type
5917458 Molecular Immunology 2011 8 Pages PDF
Abstract
► We compare antigen targeting by CD40 and FcγRII/III antibodies and by microspheres. ► All three strategies enhance antibody responses but none of the effects are additive. ► CD40 targeting induces the strongest IgG2a responses indicating a Th1 bias.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Preview
Modulation of the humoral immune response by targeting CD40 and FcγRII/III; delivery of soluble but not particulate antigen to CD40 enhances antibody responses with a Th1 bias
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