Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917471 | Molecular Immunology | 2011 | 10 Pages |
Abstract
⺠Complement factor H mRNA and protein are expressed in glial cells. ⺠Novel transcription start sites for factor H in glia and liver cells are reported. ⺠Its promoter contains enhancers and repressors affected by inflammatory cytokines. ⺠c-Jun and c-Fos can bind the factor H promoter in astrocytes.
Keywords
kiloDaltonIFN-γIL-1βc-fosAP-1MBLCFHkDaGAPDHRunx1IL-6C/EBP-βElectrophoretic mobility shift assayAstrocyteOct-1interferon-gammaInterleukin-1-betainterleukin-6rapid amplification of cDNA endstumor necrosis factor-alphaComplement factor Hbase pairc-JunCNSTranscriptionEMSA یا electrophoretic mobility shift assay central nervous systemrunt-related transcription factor 1TNF-αactivating protein-1Mannose-binding lectinComplementRacemapGATA-1Gasglyceraldehyde-3-phosphate dehydrogenase
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Authors
Laura A. Fraczek, Carol B. Martin, Brian K. Martin,