Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917481 | Molecular Immunology | 2011 | 7 Pages |
Abstract
⺠IDO mRNA and protein are expressed in human B lymphocytes when activated with CD40L and IFN-γ. ⺠TLR7/8 synergizes with CD40L + IFN-γ stimulation to enhanced IDO mRNA. ⺠The IDO expressed in human B lymphocytes is enzymatically inactive when tryptophan catabolism is measured by HPLC.
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Authors
Jessica Godin-Ethier, Laïla-Aïcha Hanafi, Jean-Baptiste Duvignaud, Denis Leclerc, Réjean Lapointe,