Article ID Journal Published Year Pages File Type
5917481 Molecular Immunology 2011 7 Pages PDF
Abstract
► IDO mRNA and protein are expressed in human B lymphocytes when activated with CD40L and IFN-γ. ► TLR7/8 synergizes with CD40L + IFN-γ stimulation to enhanced IDO mRNA. ► The IDO expressed in human B lymphocytes is enzymatically inactive when tryptophan catabolism is measured by HPLC.
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