Article ID Journal Published Year Pages File Type
5917761 Molecular Immunology 2011 9 Pages PDF
Abstract
► Here we investigated the expression of nuclear receptors (NRs) in mast cells. ► We show that Gram-negative bacteria cause upregulated NR4a expression in mast cells. ► NR4a expression is also induced by LPS and by IgE receptor cross-linking. ► NR4a expression is strongly dependent on Gö6976-sensitive kinases. ► NR4a expression is dependent on the nuclear factor of activated T-cells (NFAT) pathway.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
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