Article ID Journal Published Year Pages File Type
5917789 Molecular Immunology 2011 8 Pages PDF
Abstract
► Individual domains of Foxp3 were deleted to study their functions. ► N-terminal, leucine zipper and forkhead domains are required for Foxp3 functions. ► The zinc finger domain is only partially required for Foxp3 functions. ► The domains of Foxp3 must act together to define the features of Treg cells.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
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