Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917789 | Molecular Immunology | 2011 | 8 Pages |
Abstract
⺠Individual domains of Foxp3 were deleted to study their functions. ⺠N-terminal, leucine zipper and forkhead domains are required for Foxp3 functions. ⺠The zinc finger domain is only partially required for Foxp3 functions. ⺠The domains of Foxp3 must act together to define the features of Treg cells.
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Authors
Wei-ping Zeng, Vincent E. Sollars, Andrea Del Pilar Belalcazar,