Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917806 | Molecular Immunology | 2018 | 10 Pages |
Abstract
⺠We determined complement deposition on the polysaccharide capsule of Cryptococcus spp. ⺠C. gattii and C. neoformans activate the alternative pathway. ⺠We found a role for C4 in the alternative pathway activation by Cryptococcus spp. ⺠Alternative pathway activation by C. neoformans required both MBL-A and -C. ⺠Either MBL-A or -C was sufficient for alternative pathway activation by C. gattii.
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Authors
Kileen L. Mershon-Shier, Alex Vasuthasawat, Kazue Takahashi, Sherie L. Morrison, David O. Beenhouwer,