Article ID Journal Published Year Pages File Type
5917806 Molecular Immunology 2018 10 Pages PDF
Abstract
► We determined complement deposition on the polysaccharide capsule of Cryptococcus spp. ► C. gattii and C. neoformans activate the alternative pathway. ► We found a role for C4 in the alternative pathway activation by Cryptococcus spp. ► Alternative pathway activation by C. neoformans required both MBL-A and -C. ► Either MBL-A or -C was sufficient for alternative pathway activation by C. gattii.
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