| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5917817 | Molecular Immunology | 2011 | 10 Pages |
Abstract
- The role of DUSP1 on acute inflammatory response was investigated.
- p38 MAPK phosphorylation was limited by DUSP1.
- DUSP1 inhibited IL-6, TNF and COX2 expression in macrophages.
- Carrageenan-induced paw inflammation was enhanced in DUSP1 deficient mice.
- DUSP1 suppresses acute inflammatory response by inhibition of p38 MAPK.
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Authors
Riku Korhonen, Tuija Turpeinen, Ville Taimi, Riina Nieminen, Antonis Goulas, Eeva Moilanen,