Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5917848 | Molecular Immunology | 2011 | 6 Pages |
Abstract
- The cosignaling molecule, PD-L2 is expressed on human activated T cell subsets.
- The PD-L2 triggering down-regulates (TCR+CD28)-induced cytokine production on human T cells.
- A direct targeting of PD-L2 on T cells blocks T cell proliferation.
Keywords
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Authors
Nassima Messal, Nacer-Eddine Serriari, Sonia Pastor, Jacques A. Nunès, Daniel Olive,