Article ID Journal Published Year Pages File Type
5917848 Molecular Immunology 2011 6 Pages PDF
Abstract

- The cosignaling molecule, PD-L2 is expressed on human activated T cell subsets.
- The PD-L2 triggering down-regulates (TCR+CD28)-induced cytokine production on human T cells.
- A direct targeting of PD-L2 on T cells blocks T cell proliferation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Molecular Biology
Authors
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