Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5918053 | Molecular Immunology | 2008 | 10 Pages |
Abstract
All the V(D)J requirements were thus fulfilled when mature human CD8+ T cells were stimulated with anti-CD3 and IL7. Induction of TCR revision in vitro in mature T cells is an easily controllable system that could be employed in further studies to elucidate the molecular pathways involved in secondary V(D)J rearrangements in peripheral cells.
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Authors
Erica Lantelme, Luca Orlando, Paola Porcedda, Valentina Turinetto, Mario De Marchi, Antonio Amoroso, Stefania Mantovani, Claudia Giachino,