Article ID Journal Published Year Pages File Type
5922497 Physiology & Behavior 2016 9 Pages PDF
Abstract
CUMS-induced impairment in learning and memory could be triggered by an inflammatory response in the rat hippocampus, which results in oxidative stress injury and impacts the synaptic plasticity of hippocampal neurons. Inhibition of the activity or expression of 5-LO could suppress hippocampal inflammation, enhance synaptic plasticity, and improve learning and memory function in depressed rats.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Physiology
Authors
, , , ,