Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5922497 | Physiology & Behavior | 2016 | 9 Pages |
Abstract
CUMS-induced impairment in learning and memory could be triggered by an inflammatory response in the rat hippocampus, which results in oxidative stress injury and impacts the synaptic plasticity of hippocampal neurons. Inhibition of the activity or expression of 5-LO could suppress hippocampal inflammation, enhance synaptic plasticity, and improve learning and memory function in depressed rats.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Ying Luo, Shengnan Kuang, Lai Xue, Junqing Yang,