Silica-Bonded N-Propyl Diethylenetriamine Sulfamic Acid as a Recyclable Solid Acid Catalyst for the Synthesis of α-Aminonitriles

Silica-bonded N-propyl diethylenetriamine sulfamic acid (SBPDSA) is employed as a recyclable catalyst to synthesize a-aminonitriles. These syntheses involved one-pot condensation of an aldehyde, an amine, and trimethylsilyl cyanide under mild reaction conditions at room temperature. SBPDSA was recycled seven times in the condensation of benzaldehyde, aniline, and trimethylsilyl cyanide without reduction of its catalytic activity.

Graphical abstractα-Aminonitriles were synthesized using silica-bonded N-propyldiethylenetriamine sulfamic acid as a recyclable solid acid catalyst for condensation of an aldehyde, amine, and trimethylsilyl cyanide at room temperature.Figure optionsDownload full-size imageDownload as PowerPoint slide