Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5925004 | Physiology & Behavior | 2012 | 6 Pages |
Abstract
⺠NZW/LacJ mice eat more carbohydrate and less fat than do BTBR T+tf/J mice. ⺠A congenic line with a BTBR/NZW region introgressed on chromosome 17 was generated. ⺠The congenic mice behave like NZW mice; thus this region confers diet preference. ⺠The introgressed region contains 21 genes of which Itpr3 is a strong candidate. ⺠Perhaps a mutation in Itpr3 influences nutrient choice by disrupting taste perception.
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Authors
Michael G. Tordoff, Samira A. Jaji, Jacob M. Marks, Hillary T. Ellis,