| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5925061 | Physiology & Behavior | 2012 | 7 Pages |
Abstract
⺠We investigated the effect of castration before puberty in young mice and during adulthood in adult mice on anxiety, fear memory and extinction. ⺠We observed a significant interaction of age and hormone status on anxiety measures. ⺠Castration significantly reduced contextual fear conditioning memory. ⺠An ageâdependent difference emerged in extinction, such that the young, postpubescent mice extinguished faster than the adult mice. ⺠The results of these studies are important for PTSD and depression research.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Carmel M. McDermott, Dana Liu, Laura A. Schrader,