| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5925255 | Physiology & Behavior | 2011 | 6 Pages |
Abstract
⺠Alzheimer's disease is characterized by deficits in social communication and memory. ⺠Mutants failed to habituate and were hyperactive relative to non-transgenic. ⺠APP/PS1 mice were deficient in sociability and social memory. ⺠The 3-chamber test is useful in evaluating social anomalies in mouse models of AD. ⺠This new social paradigm, can be used to test the efficacy of experimental therapies.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Mohammed Filali, Robert Lalonde, Serge Rivest,