Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5925530 | Physiology & Behavior | 2012 | 7 Pages |
Abstract
⺠Fasting stimulated dimethylation/trimethylation of histone 3 at lysine 27 (H3K27) in brain. ⺠Fasting increased expression of the enhancer of zeste 2 (EZH2) in the PVN and PO/AH. ⺠In the PVN, CRH mRNA expression was inhibited while TRH mRNA expression was stimulated by fasting. ⺠These findings suggest a role of H3K27 methylation in epigenetic changes induced by feed stress.
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Authors
Pingwen Xu, Cynthia J. Denbow, Noam Meiri, D. Michael Denbow,