Article ID Journal Published Year Pages File Type
5925530 Physiology & Behavior 2012 7 Pages PDF
Abstract
► Fasting stimulated dimethylation/trimethylation of histone 3 at lysine 27 (H3K27) in brain. ► Fasting increased expression of the enhancer of zeste 2 (EZH2) in the PVN and PO/AH. ► In the PVN, CRH mRNA expression was inhibited while TRH mRNA expression was stimulated by fasting. ► These findings suggest a role of H3K27 methylation in epigenetic changes induced by feed stress.
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