| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5925649 | Physiology & Behavior | 2011 | 8 Pages |
Abstract
⺠High stereotypic deer mice, an animal model of OCD, have deficits in glutathione. ⺠Reduced levels of GSH and GSSG were negatively correlated with stereotypy. ⺠Increased glutathione redox index was positively correlated with stereotypy. ⺠Deficits in the glutathione system were noted in the frontal cortex but not striatum. ⺠Cortico-striatal SOD activity and striatal dopamine turnover were unaffected.
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Authors
Marianne Güldenpfennig, De Wet Wolmarans, Jan L. du Preez, Dan J. Stein, Brian H. Harvey,