Cigarette smoke dissociates inflammation and lung remodeling in OVA-sensitized and challenged mice

► We evaluated the effects of short-term cigarette smoke in ovalbumin-challenged mice. ► We hypothesized that cigarette smoke dissociates inflammation and lung remodeling. ► Mice co-exposed to OVA and cigarette smoke showed an increase in collagen content. ► The coexposure to cigarette smoke resulted in an attenuation of lung tissue elastance. ► Inflammatory cells and cytokines were diminished by coexposure to cigarette smoke.