| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5926289 | Respiratory Physiology & Neurobiology | 2012 | 7 Pages |
Abstract
⺠The medullary raphe (MR) is an important site for central chemoreception. ⺠ATP signalling has been implicated in CO2/pH sensitivity. ⺠We have examined the role of P2X receptors in the MR on CO2 respiratory responses. ⺠PPADS into the rostral, but not caudal MR, decreased the ventilatory response to CO2. ⺠P2X receptors in the rostral MR play an excitatory role in hypercapnic chemoreflex.
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Authors
Glauber S.F. da Silva, Davi J.A. Moraes, Humberto Giusti, Mirela Barros Dias, Mogens L. Glass,