| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5926292 | Respiratory Physiology & Neurobiology | 2012 | 5 Pages |
Abstract
⺠Exercise is a potent natural bronchodilator agent in healthy humans. ⺠Reduction of vagal tone has been suggested to be one of the major mechanisms. ⺠In our study bronchodilatation increased as a function of exercise hyperventilation. ⺠This was partially blunted by carvedilol, a β1-β2-adrenergic receptor blocker. ⺠Our findings suggest that β2-adrenergic receptors and airway stretching contribute to reduce bronchial tone with exercise.
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Authors
Andrea Antonelli, Roberto Torchio, Luca Bertolaccini, Alberto Terzi, Fabrizio Rolfo, Piergiuseppe Agostoni, Carlo Gulotta, Vito Brusasco, Riccardo Pellegrino,