| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5926363 | Respiratory Physiology & Neurobiology | 2012 | 7 Pages |
Abstract
⺠Whether patients with cystic fibrosis (CF) develop low frequency fatigue (LFF) of the respiratory muscles following exercise is unknown. ⺠Dynamic hyperinflation (DH) occurs during exercise in patients with CF. ⺠DH imposes both elastic and threshold loads on the inspiratory muscles and places them at a mechanical disadvantage due to muscle shortening. ⺠DH imposes a progressively resistive load and lengthens the expiratory muscles, increasing their susceptibility to develop LFF. ⺠Despite the high intensity of the exercise performed, none of the CF patients displayed evidence of LFF of the respiratory muscles post exercise.
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Authors
Charles C. Reilly, Katie Ward, Caroline J. Jolley, Lucy A. Frank, Caroline Elston, John Moxham, Gerrard F. Rafferty,