Inspiratory-activated and inspiratory-inhibited airway vagal preganglionic neurons in the ventrolateral medulla of neonatal rat are different in intrinsic electrophysiological properties

Article ID	Journal	Published Year	Pages	File Type
5926364	Respiratory Physiology & Neurobiology	2012	8 Pages	PDF

Abstract

âº Inspiratory-activated and inspiratory-inhibited AVPNs differ in architecture. âº Inspiratory-inhibited AVPNs has higher excitability under current clamp. âº Different K+ channels mediate the afterhyperpolarization in AVPNs. âº Different K+ channels mediate the voltage-gated lasting K+ currents in AVPNs.

Keywords

EPSCs CbTx SKCa large-conductance Ca2+-activated K+ channel EPSPs IPSPs DMV CNA AP5 Medulla oblongata NTS RMP IPSCs ENA PAG TTX aCSF 4-AP 4-aminopyridine 6-Cyano-7-nitroquinoxaline-2,3-dione d-2-amino-5-phosphonovalerate Apamin afterhyperpolarization tetrodotoxin excitatory postsynaptic currents inhibitory postsynaptic currents periaqueductal gray CNS Airway CNQX central nervous system AHP artificial cerebral spinal fluid nucleus ambiguus dorsal motor nucleus of the vagus action potential resting membrane potential excitatory postsynaptic potentials inhibitory postsynaptic potentials Patch clamp charybdotoxin Ion channel