Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5926429 | Respiratory Physiology & Neurobiology | 2011 | 5 Pages |
Abstract
⺠5HT1A receptors do not alter excitatory neurotransmission to cardiac vagal neurons (CVNs) under control conditions. ⺠During recovery from Hypoxia/Hypercapnia an endogenous serotonergic pathway inhibits glutamatergic transmission to CVNs. ⺠A decrease in 5-HT1A activation would augment glutamate input to CVNs causing bradycardia in diseases such as SIDS and OSA.
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Authors
Olga Dergacheva, Harriet W. Kamendi, Xin Wang, David Mendelowitz,