Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5941905 | Annals of Vascular Surgery | 2015 | 8 Pages |
Abstract
We designed and patented an original hemodynamic ex vivo model to further study new DES, as well as a wide range of vascular diseases and medical devices. This bioreactor will allow characterization of the velocity field and drug transfers within a stented artery with new functionalized DES, with experimental means not available in vivo. Another major benefit will be the reduction of animal experimentation and the opportunity to test new DES or other vascular therapeutics in human tissues (human infrapopliteal or coronary arteries collected during human donation).
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Authors
Blandine Maurel, Christophe Sarraf, Farid Bakir, Feng Chai, Mickael Maton, Jonathan Sobocinski, Adrien Hertault, Nicolas Blanchemain, Stephan Haulon, Patrick Lermusiaux,