Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5942751 | Atherosclerosis | 2016 | 6 Pages |
Abstract
Our study demonstrated an in vivo association between subcutaneous abdominal adipose tissue lipid dynamics and HDL parameters in humans, but this was true for women not men. Positive association with L-HDL and negative with I-HDL suggest that subcutaneous abdominal adipose tissue lipid dynamics may play an important role in production of mature functional HDL particles. Further studies evaluating the mechanism responsible for these associations and the observed gender differences are important and warranted to identify potential novel targets of intervention to increase the production of atheroprotective subclasses of HDL-Cs and thus decreasing the risks of development of atherosclerotic conditions.
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Authors
Demidmaa Tuvdendorj, Alejandro O. Munoz, Viviana Ruiz-Barros, Jean-Marc Schwarz, Giuseppe Montalto, Manisha Chandalia, Lawrence C. Sowers, Manfredi Rizzo, Elizabeth J. Murphy, Nicola Abate,