Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5943186 | Atherosclerosis | 2016 | 9 Pages |
Abstract
Present findings highlight the importance of tyrosine kinase pathways in the development of AAA. Our results show, that imatinib treatment inhibits essential mast cell, T lymphocyte and SMC mediated processes in experimental AAA. Thus, our results support the idea that tyrosine kinase inhibitors may be useful in the treatment of pathological vascular inflammation and remodeling in conditions like AAA.
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Emina Vorkapic, Elma Dugic, Svante Vikingsson, Joy Roy, Mikko I. Mäyränpää, Per Eriksson, Dick WÃ¥gsäter,