| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5944295 | Atherosclerosis | 2015 | 9 Pages |
Abstract
Our data show that Txnip plays an important role in oxidative inflammatory response and atherosclerotic lesion development in mice. The atheroprotective effect of Txnip ablation implicates that modulation of Txnip expression may serve as a potential target for intervention of atherosclerosis and inflammatory vascular disease.
Keywords
TrxHeme oxygenase-1CD36MCP-1VSMCHO-1GPXPAI-1TXNIPOxPAPCPrdxROSTKOAtherosclerosissmooth muscle actininflammationOxidative stressthioredoxincluster of differentiation 36SMAdihydroethidiumVascular smooth muscle cellsPlasminogen activator inhibitor-1wild typeDHERedox potentialMidpoint potentialMonocyte chemotactic protein-1Thioredoxin interacting proteinPeroxiredoxinglutathione peroxidaseReactive oxygen species
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Authors
Chang Hyun Byon, Tieyan Han, Judy Wu, Simon T. Hui,