Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5944356 | Atherosclerosis | 2015 | 11 Pages |
Abstract
PIT to fibroatheroma lesions are accompanied by early lipid accumulation, followed by macrophage infiltration with defective clearance of apoptotic bodies along with decrease in proteoglycan and hyaluronan in lipid pools that convert to necrotic cores. Calcification starts in PIT and increases with plaque progression.
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Authors
Fumiyuki Otsuka, Miranda C.A. Kramer, Pier Woudstra, Kazuyuki Yahagi, Elena Ladich, Aloke V. Finn, Robbert J. de Winter, Frank D. Kolodgie, Thomas N. Wight, Harry R. Davis, Michael Joner, Renu Virmani,