Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5945484 | Atherosclerosis | 2015 | 19 Pages |
Abstract
The effect of PCSK9 on LDLR is being successfully utilized toward the development of anti-PCSK9 therapies to reduce plasma LDL-C levels. Current biochemical research has uncovered additional mechanisms of action and interacting partners for PCSK9, and this opens the way for a more thorough understanding of the regulation, metabolism, and effects of this interesting protein.
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Authors
Hagai Tavori, Shirya Rashid, Sergio Fazio,