Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5946023 | Atherosclerosis | 2014 | 11 Pages |
Abstract
Elevated LDL-cholesterol distinguishes children with and without FH, but these groups of children also differ in several other ways. In particular, children with FH display a variety of changes reflecting both the lipid and the inflammatory arm of atherosclerosis. The IMT-meta-analysis result strengthens the evidence of early atherosclerotic development in children with FH. In a clinical perspective, early diagnosing and treatment of children with FH is of high importance to attenuate development of the potential ongoing early atherosclerotic process in these individuals.
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Authors
Ingunn Narverud, Kjetil Retterstøl, Per Ole Iversen, Bente Halvorsen, Thor Ueland, Stine M. Ulven, Leiv Ose, Pål Aukrust, Marit B. Veierød, Kirsten B. Holven,