| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5947115 | Atherosclerosis | 2013 | 7 Pages |
Abstract
⺠Acrolein-conjugated LDL (Acro-LDL) was prepared by incubation of LDL with acrolein. ⺠The mobility of Acro-LDL determined by agarose gel electrophoresis was increased. ⺠Acro-LDL-induced higher cholesterol accumulation in macrophages than oxidized LDL. ⺠Acro-LDL uptake was mediated by scavenger receptor class A type 1 (SR-A1). ⺠Cholesterol in Acro-LDL was accumulated in lipid droplets of macrophages.
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Authors
Kenta Watanabe, Yuki Nakazato, Ryotaro Saiki, Kazuei Igarashi, Mitsukazu Kitada, Itsuko Ishii,