HDL protects against ischemia reperfusion injury by preserving mitochondrial integrity

Article ID	Journal	Published Year	Pages	File Type
5947626	Atherosclerosis	2013	7 Pages	PDF

Abstract

âº HDL protect against lethal ischemia reperfusion injury. âº HDL induce cardioprotection by preserving mitochondrial integrity. âº TNFÎ± and STAT3 are required for HDL-induced cardioprotection.

Keywords

STAT3 HDL MPTP VDAC TNF IRI Ischemia reperfusion injury mitochondrial permeability transition pore SAFE tumor necrosis factor alpha high density lipoproteins signal transducer and activator of transcription 3

Related Topics

Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine

Preview

HDL protects against ischemia reperfusion injury by preserving mitochondrial integrity

Authors

Miguel A. Frias, Sarah Pedretti, Damian Hacking, Sarin Somers, Lydia Lacerda, Lionel H. Opie, Richard W. James, Sandrine Lecour,