Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948054 | Atherosclerosis | 2012 | 7 Pages |
Abstract
⺠Expression of Tim-3 increase on NK cells, but not T cells, in AS patients. ⺠Augmented expression of Tim-3 on NK cells correlates with risk factors of AS. ⺠Augmented expression of Tim-3 inhibits NK cells survival in vitro. ⺠Blockade of Tim-3 protects NK cells from TNF-α-induced cell death. ⺠Augmented Tim-3 expression on NK cells plays an important role in NK cell loss in atherosclerosis.
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Authors
Nan Hou, Di Zhao, Ying Liu, Lifen Gao, Xiaohong Liang, Xiao Liu, Xiaoxiao Gai, Xiaoning Zhang, Faliang Zhu, Mei Ni, Yun Zhang, Wensheng Sun, Chunhong Ma,