Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948164 | Atherosclerosis | 2012 | 7 Pages |
Abstract
⺠Animal study investigating mTOR-inhibition for treatment of advanced atherosclerosis. ⺠Everolimus reduced inflammatory cell content locally but pre-existing atherosclerosis progressed obstructively. ⺠Anti-atherosclerotic efficiency of pharmacotherapeutic mTOR-inhibition is suggested stage-dependent. ⺠Higher potential might be obscured by concomitant hypercholesterolemia.
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Authors
Frank Beutner, Désiré Brendel, Daniel Teupser, Kristina Sass, Ronny Baber, Marc Mueller, Uta Ceglarek, Joachim Thiery,