Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948249 | Atherosclerosis | 2012 | 7 Pages |
Abstract
⺠We evaluated clinical factors that influence CYP-derived eicosanoids in CAD patients. ⺠Obesity and advancing age were associated with lower EET levels. ⺠Obesity and cigarette smoking were associated with lower epoxide:diol ratios. ⺠Renin-angiotensin system inhibitor use was associated with lower 20-HETE levels. ⺠CAD patients exhibited lower sEH metabolic activity relative to healthy individuals.
Keywords
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Authors
Katherine N. Theken, Robert N. Schuck, Matthew L. Edin, Bryant Tran, Kyle Ellis, Almasa Bass, Fred B. Lih, Kenneth B. Tomer, Samuel M. Poloyac, Michael C. Wu, Alan L. Hinderliter, Darryl C. Zeldin, George A. Stouffer, Craig R. Lee,