Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948308 | Atherosclerosis | 2012 | 7 Pages |
Abstract
⺠The leptin sensitivity is preserved for an extended period of time in lean T1D. ⺠Leptin replacement alone inhibits the progression of atherosclerosis in T1D. ⺠Physiologic leptin replacement exerts cholesterol-lowering effect in T1D. ⺠Leptin therapy restores the decreased expression of hepatic IRS-1 and -2 in T1D.
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Authors
John Y. Jun, Zhexi Ma, Rajkumar Pyla, Lakshman Segar,