Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948318 | Atherosclerosis | 2012 | 9 Pages |
Abstract
⺠We compared ezetimibe add-on to statin effects on lipids/non-cholesterol sterols. ⺠High-potency statin group (HPS) had lowest lathosterol/highest sitosterol at baseline. ⺠HPS + ezetimibe had the greatest absorption reduction/smallest synthesis increase. ⺠LDL-C lowering was similar for ezetimibe add-on to low-/medium-/high-potency statins. ⺠Results highlight complementary effect of statin + ezetimibe on synthesis/absorption.
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Authors
Nuntakorn Thongtang, Jianxin Lin, Ernst J. Schaefer, Robert S. Lowe, Joanne E. Tomassini, Arvind K. Shah, Andrew M. Tershakovec,