Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5948698 | Atherosclerosis | 2012 | 9 Pages |
Abstract
⺠Lympatic vessels can be found in human stenotic aortic valves. ⺠Lymphangiogenic growth factors VEGF-C and VEGF-D are locally produced. ⺠Myofibroblasts and endothelial cells are their possible sources in aortic valves. ⺠Mast cells can both induce the expression of VEGF-C and degrade the protein. ⺠Imbalance between lymphatic and blood vessels may promote disease progression.
Keywords
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Authors
Suvi Syväranta, Satu Helske, Jani Lappalainen, Markku Kupari, Petri T. Kovanen,