| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5948704 | Atherosclerosis | 2012 | 8 Pages |
Abstract
⺠The first report on the cholesterol-lowering activity of isolated docosahexaenoic acid (DPA) n-3 and DPA n-6. ⺠DPA n-3, DPA n-6 and docosahexaenoic acid (DHA) all reduced plasma cholesterol in hamsters fed a high cholesterol diet. ⺠Reduction in plasma cholesterol was accompanied by down-regulation of SREBP-2 and HMG-CoA reductase. ⺠DPA n-3 and DHA improved the aortic function mediated by down-regulation of COX-2.
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Authors
Jingnan Chen, Yue Jiang, Yintong Liang, Xiaoyu Tian, Cheng Peng, Ka Ying Ma, Jian Liu, Yu Huang, Zhen-Yu Chen,