| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5949040 | Atherosclerosis | 2012 | 7 Pages |
Abstract
Poly-IgM treatment reduced aortic and accelerated carotid atherosclerosis in apoEâ/â mice in association with increased anti-oxLDL IgG titers, and reduced number and proliferative function of splenic CD4+ T cells. Our study identifies a novel athero-protective and immunomodulatory role for non-immune polyclonal IgM.
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Authors
Fernando H.Y. Cesena, Paul C. Dimayuga, Juliana Yano, Xiaoning Zhao, Jonathan Kirzner, Jianchang Zhou, Lai Fan Chan, Wai Man Lio, Bojan Cercek, Prediman K. Shah, Kuang-Yuh Chyu,