Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5949182 | Atherosclerosis | 2011 | 7 Pages |
Abstract
Due the potent endothelial cell death inducing activity of UA, a systemic application of UA in the treatment of cardiovascular diseases seems unfavourable. UA as an anti-angiogenesis, anti-cancer and - locally applied - cardiovascular drug may be helpful. The DNA damaging activity of UA may however constitute a serious problem.
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Authors
Barbara Messner, Iris Zeller, Christian Ploner, Sandra Frotschnig, Thomas Ringer, Anneliese Steinacher-Nigisch, Andreas Ritsch, Günther Laufer, Christian Huck, David Bernhard,