Efficient solvent-free synthesis of pyridopyrazine and quinoxaline derivatives using copper-DiAmSar complex anchored on SBA-15 as a reusable catalyst

A catalytic system comprising mesoporous silica functionalized with Cu(II)-DiAmSar was synthesized. This was demonstrated as an efficient heterogeneous catalyst for the synthesis of biologically useful pyridopyrazine and quinoxaline heterocycles under solvent-free conditions. X-ray diffraction, transmission electron microscopy, N2 adsorption-desorption, Fourtier transformation infrared spectroscopy, and thermogravimetric analysis were used to characterize the catalyst and investigate the texture of SBA-15 during the grafting process.

Graphical AbstractA silica-based mesoporous organic–inorganic hybrid catalyst was synthesized by anchoring Cu(II)-DiAmSar on SBA-15, which gave high activity for the synthesise of pyridopyrazine and quinoxaline derivatives under solvent-free conditions.Figure optionsDownload full-size imageDownload as PowerPoint slide