| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5952491 | Chest | 2016 | 30 Pages |
Abstract
During AECOPD, there is increased expression of heparan sulfate and chondroitin sulfate in BAL. These molecules are significantly correlated with MMPs in BAL, indicating that they may be associated with airway remodeling and may lead to lung function decline during exacerbations of COPD.
Keywords
MMPGAGICSAECOPDECMLAMAlong-acting muscarinic antagonistLong-acting β2-agonistAirway inflammationAirway obstructionCOPDELISAEnzyme-linked immunosorbent assayacute exacerbation of COPDResidual volumeLABAcoefficient of variabilitybronchoalveolar lavageExtracellular matrixmatrix metalloproteinaseInhaled corticosteroidGlycosaminoglycan
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Authors
Eleni MD, PhD, Ioannis PhD, Michael PhD, Michael MD, Daiana MD,