Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5953473 | Chest | 2015 | 10 Pages |
Abstract
Age, sex, baseline functional capacity, and disease etiology are variably associated with the likelihood of achieving clinically relevant responses in patient-important outcomes to PAH-specific therapy such as 6MWD and HRQoL. The increased likelihood of response in men compared with women is a novel finding and may reflect pathophysiologic differences between sexes.
Keywords
PAHMIDSF-36MCscGMPCTDET-1HRQOLSGC6-min walk distance6-min walk test6MWTendothelin receptor antagonistendothelin-1Connective tissue diseaseMinimal important differencephysical component summarymental component summaryPCsSoluble guanylate cyclaseERAPulmonary arterial hypertensioncyclic guanosine monophosphateMedical Outcomes Study Short Form-36Nitric oxideHealth-related quality of life
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Authors
Stephen C. MD, MHS, FCCP, Paul M. MD, FCCP, Milo A. MD, PhD, Yi PhD, Robert A. MD, FCCP,