Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5954783 | Chest | 2014 | 13 Pages |
Abstract
Incidence rates of IS/TE, mortality, and bleeding increased with reducing eGFR across the whole range of renal function. OAC use was associated with a lower incidence of IS/TE and mortality at 1 year compared with individuals not receiving anticoagulants in all categories of renal function as measured by eGFR. The NCB balancing IS against serious bleeding was positive in favor of OAC use among patients with renal impairment.
Keywords
EGFROACHAS-BLEDATRIANVAFCHADS2NCBMDRDVKACHA2DS2-VAScvitamin K antagonistmodification of diet in renal diseasechronic kidney diseaseThromboembolismintracerebral hemorrhageIschemic strokeOral anticoagulationAtrial fibrillationNonvalvular atrial fibrillationNet clinical benefitICHestimated glomerular filtration rateCKD
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Authors
Amitava MPH, DPhil, Laurent MD, PhD, Patrick PhD, Christian R. MD, PhD, Sophie MD, Jean Michel MD, PhD, Gregory Y.H. MD,