| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5955184 | Chest | 2013 | 7 Pages |
Abstract
Glut-1 transporter expression in normal lung is limited to erythrocytes. In fibrotic lung, erythrocytes and inflammatory cells express Glut-1. Together, these data suggest that FDG-PET scan uptake in IPF could be explained by enhanced inflammatory and erythrocytes uptake due to neovascularization seen in IPF and not an upregulation of metabolic rate in pneumocytes. Thus, FDG-PET scan may detect inflammation and neovascularization in lung fibrosis.
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Authors
Souheil MD, MPH, Daniela MD, PhD, Jianhua PhD, Steven D. MD, FCCP, Ivan O. MD, William A. MD, Joel MD, PhD, FCCP, Bernadette R. MD,