| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5960272 | Heart Rhythm | 2014 | 7 Pages |
Abstract
No very rare AAC variants were identified in ~80% of lone AF probands. Potential reasons for the lack of very rare AAC variants include a complex pattern of inheritance, variants in as yet unidentified AF genes or in noncoding regions, and environmental factors.
Keywords
LVESDLVEDdExome Sequencing ProjectLVEFESPIQRAACMAFECGelectrocardiogramrare variantsGenetic epidemiologyGenetic variationbody mass indexBMIminor allele frequencyAtrial fibrillationleft ventricular end-diastolic diameterleft ventricular end-systolic diameterinterquartile rangeFamily studyGenome-wide association studyGWASProarrhythmiaSingle nucleotide polymorphismSNPCandidate genesleft ventricular ejection fraction
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Authors
Peter MD, Babar MD, Marcia MS, Laura MS, Christie BS, Gayle RN, Tanya RN, Dan M. MD, FHRS, Dawood MD, FHRS,