| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5960629 | Heart Rhythm | 2014 | 9 Pages |
Abstract
Induction of KCNQ1 autoimmunity accelerates cardiac repolarization and increases susceptibility to ventricular tachyarrhythmia induction through IKs enhancement. On the other hand, vaccination against KCNQ1 ameliorates drug-induced QTc prolongation and might be useful therapeutically to enhance repolarization reserve in long QT syndrome.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Jin MD, Ange PhD, James Elber Duverger, Patrick MSc, Philippe PhD, Yanfen PhD, Jean-Claude MD, Dierk MD, FAHA, FESC, FHRS, Stanley MD, FRSC, FRCPC, FACC, FHRS,